WEAR STUDY - Biosensors
Get ready! We’re about to start our new VIBRANT biosensor study (Validating Innovative Biosensors in Rett for AutoNomic Symptom Tracking)! The VIBRANT study will take place at Boston Children’s Hospital, Rush University, and Baylor College of Medicine/Texas Children’s Hospital to test several wearable FDA-cleared biosensors and the freestanding invisible Emerald sensor. The purpose of the study is to create reliable objective measurements of Rett syndrome symptoms for clinical trials, including sleep, breathing, heart rate, and oxygen saturation. Emerald will also be used to develop the ability to measure movement in Rett. Your participation could help revolutionize how we test the effectiveness of treatments for Rett.
This study is for individuals who need an overnight sleep study in a sleep lab. The VIBRANT study involves one in-person visit to get the biosensors, wearing the biosensors during their overnight stay in the sleep lab, and up to 9 weeks of at-home data collection. The wearable sensors will be worn between 2 and 4 days a week for 4 weeks with data available for parents to learn more about their child’s symptoms. The Emerald will collect data on sleep and breathing every night, and will collect movement information a few times a week for up to 9 weeks. Caregivers will answer questions electronically each day about their child’s health. At the end of the 9-week study period, the biosensors will be mailed back to the site and parents can get a report of their child’s Emerald data.
This study is currently enrolling a small number of participants. To be eligible, you must be able to travel to the participating site and have a child at least 4 years old diagnosed with Rett syndrome confirmed by a genetic mutation in the MECP2 gene. Additional requirements apply. To learn more or be contacted by a research coordinator for the study to determine your eligibility, sign up below.